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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89ee709fb0c94331e128f9a64b2dba506f6485cbea81751a52c8f70cc4d3dfae' 
  AND token = 'l+bSIp2vJ+kijaY3Rhtb25Y3lyZGyqHHnlBtRx7N7xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}