SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c57fe9887f05479bb6ccbe705f3f7f0ad7aa165df9549289f178c2394cd85abb' 
  AND token = '2n7/NGSqKauzBpgTy9dBk5bcACSTnI9pBk80gS7MRz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}