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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cf9936e378a88d9ccfdc2d09837e76473aeb8c9123de673b88d63ce735d87a0' 
  AND token = 'J+2P2f+KwGch+yoyPK+tPUS8lh/Qkf6oiNv6YNHV+mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}