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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6497cbc30308c7cdb16a42c1e88add3cada0855e5ee8f35fb4c6ab0a2d5df81' 
  AND token = 'l3eOsxoIOHyMCK+xOq9QAyZIB9teN54A5row37pH9SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}