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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '197b8c5acec3186a2103d964d9f8dd6ca9218c1eb03c9911f113439336d27f2c' 
  AND token = '5tpAz7uZXHwLrmaF0wx8SM+Cr0eSMK3RTCprrWHO3c8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}