SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4394b3abd0cf79b7bdce95da852946ca4bcf6eede06e9a43e89bb4f0adc6ae82' 
  AND token = 'IIZFi5ZxDjINixRfv8RF3k/wR4SHTMRL/Cvr3QXDx5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}