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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '625b49d454c2745bc5d907d82d6885862c22e7d5e1a0c799d9e437bc68761e6d' 
  AND token = 'Wn4u6WQ+G3HT3UtHqUCV2VBYtnlyT1cRwIdWK77D92g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}