SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c8330c39e8bb119efe29e3aacbf44fb441bcffe6bc29c36c9dd13c6d9c496f4' 
  AND token = 'avoVrbm9SP0ckHFOHzQyuovYO++SUEpdsx0CStsn8Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}