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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e62230e862eda5a3521cfb40c2377afa533a2f04b96f81ae7b4e07674a1538' 
  AND token = 'wAQ6MRk0IrUTGYqcFc8jk0an9CV9VqeUbxKrF0kVwJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}