SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ca31ee5138f40b504adbe982f2e533dae1d0b655c1509a9945d55f926475a3' 
  AND token = 'qG5noLY2MECpDuhlIhFCMW6QgFbhTDmvsr8eOHkXHRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}