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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d66d44ba418890de2e34f131f44d336ddfcac648a79f98dd8ed1d83c928b49' 
  AND token = '3mkl0jZq9rtYHUyAd1dmFE6jILw2PVveTNy5yiRmpew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}