SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d42994c3c09a6e06c0665f10ccff34b59ff6b879c21ab47a05357158f42b7f' 
  AND token = 'F7WwRpRDYqGNZOKNw+PYnE1w4+HWIAanes5BDyycwUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}