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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c9030ca21b8a390a64e3b99a94f5f75f25dd4150d55e974f02b542d78645131' 
  AND token = 'EGRUAotJEOoC7tlBtwUgh9jdsI7XSuYIQ6PuHOnrSaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}