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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19ac308e0c35e39d396ab821ad9090e4ca9283b792573717127bf8ea1a147229' 
  AND token = 'F9R7KD+sozl9RLXRmUD5HOqWOcOdIxehIvK72F2+WSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}