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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35534069ee8940f86cdd2b37b46821455566111f6df5bbd26c4552205ad1d385' 
  AND token = 'MzmPJ2ogbR/hFnVdMv7vKO/L6/czWUCS3FiMJFUEdKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}