SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afeff92faf7cd9205bc16cb9d75a109de6a2463cb0213eb423975324dd38df2d' 
  AND token = '1CyRD6uDJEfNL2uHqBESjrmSLudYvuDRvA5Cg4FzVK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}