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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1caed1eb9b5447e382a60e2af588f69219be37eed241d489a0e6546c2759258a' 
  AND token = '4BJQtX5C8KDMhE7Bj2RDAUb67UDYYgEpGiIIdFUDU/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}