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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5a161cc8ed6993048cc956658f049153ce2bc1d06589e93b64f04e55affd52a' 
  AND token = 'hjdk0NGgaH7TSC0lGQJ7QdmLzT8mOBOaePKAq1kOHJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}