SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80be5055401f030a14e8b7060907ac1be1bf97378d9f13275b86cd4b5d4ac8d7' 
  AND token = '71aU05YVBKFWofY2KBIpOGmoXmEr2zwVnGWn2E8DJOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}