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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f7a0271debe17e63abd5bce41a0ac190eae82dc53bb9fc77222cfb9cf32220' 
  AND token = 'VgtHAF+mBmDgnvqn4AU32S57Wj7m5swVkIR8I9Vp+TE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}