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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c3150a048192b7dcf30980addd94d181059d70e18a1ab75f261f0127b9e64ed' 
  AND token = 'fZhquKagcZCmVTR2lHIpCHIEtB083RXU0/e1ZY4GONM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}