SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9172bddfb367bd19eeb62a9da624e1eecc2b2fd5da229591f2149dda6e0da55' 
  AND token = 'EXP26M1/TAc3U6C5Nf6l1pluKGnE0nhVzi5KczNcO/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}