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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f08e8792b811e7439463700c1007110ef27f02cc4d13c2ba89e9c11d9046a2e' 
  AND token = 'IAXoqy7rBKq5fQ3A+xX0xNvmHfNAruz3WLMV9rtqi7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}