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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fdd4d1e491d920e98b7ecf99b9e50789c38664f598fa9005aa1135dac14180d' 
  AND token = 'zbniu3ib+lLaAMLUHrzjhR4JvdiriqCYqc+ds+8Pkks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}