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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27cf234935cb7ad4d819fce7f94fcc2d8a8ed070f84badf5275595d98bad1527' 
  AND token = 'qm24XW6BAscif30GY8IvIK4HoiM/ZbElDK7+hetDghs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}