SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bdde5f798e8491d33c7fb24ddd2773d42b23368139d54fc7f211126cc25db57' 
  AND token = '1nTsFZSBEUM9KkPE9Or3sqDT5DhtVUsCSEVolszUDbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}