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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4550dc5de4bab87b53c5a1b0d178156cca300278dc18ff34e86db9623bd25305' 
  AND token = 'Ji5X/SlknZEPapgt5+QRdfBsCx8oGkYFHwvlalZv4Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}