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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa04b374e01954e35ca512ed7d7dd536dffd9400e7870da81d4d2e67d0757221' 
  AND token = 'H0a1Th7Yl/I/YmeCBm+Kzrs8kcxIVcv0Gu0o2MHteFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}