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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e0a699dd61375fbb3009380cbd2ba27b1a123d3802387f41bd04c0122d6d04d' 
  AND token = 'eZxHSqZGyEKKUtP7g9lkK75sLD0tQCKXWsWoGiVVOm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}