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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a21d09b4517ba7e8f56a7bf6696f9f83e925d83efdc8e2e304529b4de5c99209' 
  AND token = 'Vv5cC9l03/aLEUt3jlgglWIXL3AhmHLip7aalDGSgiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}