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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f48ac3d249148a6bda5845c824904a8c073aa2f54d5cd873155e1771b7e6fc4' 
  AND token = 'Nfbywn9f4ZU1+ghoxGUJ3Qvy5OUbDKf3yMr0I8dyIG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}