SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff95f7429710065cfcc8df4bd264e19d81e197db26d492033f35d188d66f6b6a' 
  AND token = 'b3EuGGMX049dF2r+n3V0lMy7lyACutXkzupz3qqNQ88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}