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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4722a5aab38b1dd7ac72b4457bda1bf1f3d9ce13d1e34c81649927832d16641a' 
  AND token = '0O8CVYYRjCPZSi76WuH/a99SnZawIyvfG66WICAxDbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}