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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b148fd00b90d98a1a304f2e674bc347f3359d934d8f903b51fd1203efc699170' 
  AND token = 'jC2UOmjF8Dbo5iujcs4bZTTNHms6RyorPTKebxN7IEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}