SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74ea6416137ac40b7eacaa93271fc02c837bd1dfe308a4025d3110e03a5a31a4' 
  AND token = 'OyQPk8zqarAsErBXB+JearOFhY4rIWaaJlZNWySdpBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}