SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '787b0413da84d774b59d2b5c022bbd2f88105e93c89fe85826b10a55299aa980' 
  AND token = '6Vs4/nluPVjT5EFttbJmsZGeFN5iNuBJNkz7UkFFUlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}