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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ff5540a9550b00c395df4652a2a8bfb901637be4450534c5e31f11602c580bb' 
  AND token = 'xZdkSOg3jP+0ejP/s1L362LDW7mxzUQdhY/ITSKRUzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}