SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0483621ac6f04c9e1c2a98174bcba37f2e33fa42f55ed60067e7314048b49fce' 
  AND token = 'xTFgOp3LhSbZDeyp6jL0qel9ieddswTNrx2vMgL9LEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}