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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '675c6375ca7e392eeb5bc84b9a9e6f6841edb16f5a491d2ae3f070d658a6d9fb' 
  AND token = 'FQw/avZZ/p/oxo67v6VgLNIsvkbe/uPSKkk3nFgRwIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}