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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01040e5a9e0f7f810e4eb6fdeb24bf6a64f80de00d576fa3524d512915e0b057' 
  AND token = 'HF53pbhW5KoxSsJD8hW7RIT0zjf+HxJzaRUFj5CvcZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}