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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3510dc5dfc87008cde32d0c6de12fad6ed292bea1b5bd8904576bc236a31711' 
  AND token = 'jjbEM3oodKLwSMqMxUxLdXi8jYO4KPWsBYT2nyyfUD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}