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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '783434d454c548b4986ed803f7df9eb3696227ed530b53952badfa1f2f211ab5' 
  AND token = '1FnGFFZR6MFq4M9AQ0TdPNw13DITRNtTzU6Q29lIH+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}