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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34c346868d75e4e3539a3533a0cef39fc44a3c81a36815e8241ed4c6c55743fb' 
  AND token = 'CRvFUKOzkxuhsRMTMoLWjajE0yP5zUS34bRy7Eki2+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}