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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b3c9270a79e14d49cd75a79237dff1d58755458c3025278dbee7b3f08e112b1' 
  AND token = '1ZrFUj3PP96avwMf0vLoOQGrrLAtG3eOc+CiV+elDsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}