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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e246728b11ef9e6fea9006094c6e91889f368f2713f52008279bbd96da230dba' 
  AND token = 'Py8CmIojvXeE3rUp3r/DTDqJnJLyhO4Uv5qSKUU5u6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}