SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb83358ca5bc5d7b5a538b6850b9e6aede87037cbfaafb683a33697a83b890f' 
  AND token = 'EpyiP0JJFFoiNKyXoGt0laclUkAqMNPpWqINJlsuZ0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}