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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b40de8a2b752dd6d14a72e1d47aa7b607b2f7d07edb53cb1948c6497397a4b' 
  AND token = '2i1v0heQWugrWF9Su4YX02KrHCWtOA1HWuJmet+qMrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}