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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ff2330ee7297b52a8cafa1d8b7d04eaead61cd919d8e6c6262f9a024dd185b' 
  AND token = 'mfUsfm8/7g17r5XsD1E2GLfza4wgkaw7hlMIAlBd+qQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}