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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '115bb0dd7fd974b3644f5b1c86232926266cb93f3732d24760d4155db2d21175' 
  AND token = 'SCkyu83P/z6N4fTlW1ZKZkfgkzu2SIUJtMZ5TLndcf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}