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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7bb575ad349838696ab466fcdee13bd9782fcdd1d20e25100ec72fef67d2502' 
  AND token = 'C+EeFc/1G1r9Z1NBL+9uVVf+0Q+02xc1T9eDsEkHyNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}